ENGLISH
Abbott
MEDICINE

CML is a myeloproliferative disease that develops at the time the Philadelphia chromosome appears. It presents an abnormal proliferation of immature granulocytic cells that are displacing the normal cellular population. Its treatment is based on administration of oral tyrosine kinase inhibitors. Adherence is critical to achieving disease control.

It is indicated for the treatment of adults with: chronic myeloid leukemia (lmc) with Philadelphia chromosome positive (ph +) in chronic phase of recent diagnosis. Lmc ph + in chronic, accelerated, or myeloblastic or lymphoblastic phase with resistance or intolerance to previous treatment, including imatinib. Acute lymphoblastic leukemia with Philadelfia chromosome positive (lla ph +) with resistance or intolerance to previous treatment.

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